GlauCAT™️ is a suite of computerised adaptive tests (CATs) that measure the impact of glaucoma on 12 domains of quality of life.
Ocular comfort symptoms
GlauCAT™️ - Asian
GlauCAT™️ – Asian is a suite of computerised adaptive tests (CATs) that measure the impact of glaucoma on 7 domains of quality of life.
Ocular comfort symptoms
The GlauCAT™️ instruments comprise hundreds of items in calibrated item banks. Using CAT (a type of artificial intelligence) the GlauCAT™️ systems iteratively select items that most closely match the person’s quality of life at that point in the test. This “smart-technology” means that patients answer only a small number of items and scores are generated in ~2 minutes per domain.
With a user-friendly interface and automated feedback system, the GlauCAT™️ systems offer researchers, clinicians and clinical trial teams a precise, efficient and culturally applicable PROM to evaluate the effectiveness of treatment therapies, including topical medications, laser, and surgery, from the patient’s perspective.
GlauCAT™️ domain and item development and refinement
GlauCAT™️ - Asian domain and item development and refinement
Psychometric testing of GlauCAT™️ item banks using data from 293 patients with glaucoma.
The GlauCAT™️ item banks were used in the Glaucoma Initial Treatment Study to compare this impact of topical medication and selective laser trabeculoplasty as initial glaucoma treatment.
GlauCAT™️ is currently being used in a clinical trial in patients with glaucoma to measure the impact of Minimally Invasive Glaucoma Surgery (MIGS) on quality of life at the Singapore National Eye Centre.
GlauCAT™️ is currently being used in an observational investigation by Perfuse Therapeutics of patients with open angle glaucoma and progressive visual field loss to understand the natural history of the condition and its impact on quality of life.
Researchers at the Wilmer Eye Institute are currently assessing patient experience with the GlauCAT™️ test administration process to determine the most practical way to employ the test and to what extent testing needs to be customised, as well as exploring what QoL domains are most affected in glaucoma patients across the severity of the condition.
Glaucoma Utility instrument (Glau-U)
Glau-U is a preference-based utility instrument that can differentiate between
glaucoma severity and vision impairment levels.
Patients rate their difficulty on six aspects of glaucoma-specific QoL and scores
are converted to utilities using utility weights.