Our diabetic retinopathy-specific PROMs provide comprehensive and valid measurement of quality of life and other outcomes relating to diabetic retinopathy and diabetic macular edema, and associated vision impairment and treatments.
RetCAT™️
RetCAT™️ is a suite of computerised adaptive tests (CATs) that measure the impact of diabetic retinopathy and diabetic macular edema on 10 domains of quality of life.
Visual symptoms
Activity limitation
Mobility
Emotional
Concerns
Social
Convenience
Economic
Driving
Lighting
RetCAT™️ comprises over 250 items in calibrated item banks. Using CAT (a type of artificial intelligence) the RetCAT™️ system iteratively selects items that most closely match the person’s quality of life at that point in the test. This “smart-technology” means that patients answer only a small number of items and scores are generated in ~2 minutes per domain.
With a user-friendly interface and automated feedback system, RetCAT™️ offers researchers, clinicians and clinical trial teams a precise and efficient PROM to evaluate the effectiveness of treatments and interventions, including laser therapy and intravitreal injections, from the patient’s perspective.
Publications
Domain and item development
Content refinement
Psychometric testing of item banks using data from over 500 patients with DR/DME.
CAT platform development and evaluation of RetCAT using data from 180 patients with DR.
RetCAT™️ is currently being used in a clinical trial in patients with DME to measure the impact of intravitreal injections on quality of life at the Singapore National Eye Centre.
Diabetic Retinopathy Utility instrument (DR-U)
DR-U is a preference-based utility instrument that can differentiate between levels of diabetic retinopathy severity and related vision impairment.
Patients rate their difficulty on five aspects of diabetic retinopathy-specific QoL and scores are converted to utilities using utility weights
Visual symptoms
Lighting and glare
Activity limitation and mobility
Socio-emotional well-being
Inconvenience
Main Publication
DR-U enables researchers to measure health utilities associated with diabetic retinopathy and changes following treatment interventions. DR-U is suitable for economic analyses relating to diabetic retinopathy treatments, informing health policies related to personnel, resources and funding allocated to late-stage diabetic retinopathy, eye care and rehabilitation.
Diabetic Retinopathy Knowledge and Attitudes (DRKA) questionnaire
Main Publication
The DRKA questionnaire was developed to measure patients’ understanding of and attitudes about the development and progression of diabetic retinopathy, and treatment and management regimens and goals.
Based on the Knowledge-Attitudes-Practice-Outcomes (KAP-O) Framework, the DRKA comprises two separately scored Knowledge and Attitudes domains.
The DRKA offers researchers and clinicians a valid and relevant PROM to measure levels of knowledge and attitudes in patients with diabetes and diabetic retinopathy, and to assess the effectiveness of educational interventions to improve knowledge, attitudes and practice.